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For example, statins have been implicated in directly causing immune-mediated necrotizing myopathy thought to be caused by upregulation of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR), the molecular target of statins, resulting in presentation of highly immunogenic HMGCR peptides by human leukocyte antigens

On Friday, a spokesperson for the Department of Health and Human Services (HHS) told Newsweek that the FDA convened the Pharmacy Compounding Advisory Committee to evaluate available evidence, including newly submitted information, on the peptides' potential benefits, risks and safety

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Est distribuida de forma desigual entre los tejidos y rganos, con un 80% presente en los msculos y un 5-10% en el tracto digestivo